Partial characterization of thyroid stimulating hormone in thyroid tumors using radioligand binding assay techniques

Abstract

Thyroid Stimulating Hormone (TSH) plays a crucial role in regulating thyroid function and is implicated in various thyroid disorders, including tumors. This study aims to partially characterize TSH in thyroid tumors using radioligand binding assay techniques. By employing specific radiolabeled TSH ligands, we evaluated the binding affinity and kinetics of TSH in tumor tissues compared to normal thyroid tissues. Our findings indicate significant differences in TSH receptor expression and binding characteristics in tumor samples, suggesting altered TSH signaling pathways in thyroid tumors.